Human Peripheral and Umbilical Cord Blood Identification of a Novel Hierarchy of Endothelial Progenitor Cells Utilizing

نویسندگان

  • Mervin C Yoder
  • David A Ingram
  • Laura E Mead
  • Hiromi Tanaka
  • Virginia Meade
  • Amy Fenoglio
  • David A. Ingram
  • Laura E. Mead
  • Kelly Mortell
  • Karen Pollok
  • Michael J. Ferkowicz
  • David Gilley
  • Mervin C. Yoder
چکیده

(2497 articles) Hemostasis, Thrombosis, and Vascular Biology • (3094 articles) Hematopoiesis and Stem Cells • Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#reprints Information about ordering reprints may be found online at: http://bloodjournal.hematologylibrary.org/site/subscriptions/index.xhtml Information about subscriptions and ASH membership may be found online at:

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Identification of a Novel Hierarchy of Endothelial Progenitor Cells Utilizing Human Peripheral and Umbilical Cord Blood

Emerging evidence to support the use of endothelial progenitor cells (EPC) for angiogenic therapies or as biomarkers to assess cardiovascular disease risk and progression is compelling. However, there is no uniform definition of an EPC, which makes interpretation of these studies difficult. Though a hallmark of stem and progenitor cells is their ability to proliferate and give rise to functiona...

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Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells.

Endothelial progenitor cells (EPCs) can be isolated from adult peripheral and umbilical cord blood and expanded exponentially ex vivo. In contrast, human umbilical vein endothelial cells (HUVECs) or human aortic endothelial cells (HAECs) derived from vessel walls are widely considered to be differentiated, mature endothelial cells (ECs). However, similar to adult- and cord blood-derived EPCs, H...

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HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

Emerging evidence to support the use of endothelial progenitor cells (EPCs) for angiogenic therapies or as biomarkers to assess cardiovascular disease risk and progression is compelling. However, there is no uniform definition of an EPC, which makes interpretation of these studies difficult. Although hallmarks of stem and progenitor cells are their ability to proliferate and to give rise to fun...

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Hemostasis, Thrombosis, and Vascular Biology

Endothelial progenitor cells (EPCs) can be isolated from adult peripheral and umbilical cord blood and expanded exponentially ex vivo. In contrast, human umbilical vein endothelial cells (HUVECs) or human aortic endothelial cells (HAECs) derived from vessel walls are widely considered to be differentiated, mature endothelial cells (ECs). However, similar to adultand cord blood–derived EPCs, HUV...

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Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood.

Emerging evidence to support the use of endothelial progenitor cells (EPCs) for angiogenic therapies or as biomarkers to assess cardiovascular disease risk and progression is compelling. However, there is no uniform definition of an EPC, which makes interpretation of these studies difficult. Although hallmarks of stem and progenitor cells are their ability to proliferate and to give rise to fun...

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A New Two Step Induction Protocol for Neural Differentiation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells

Background: In this study, we examined a new two step induction protocol for improving the differentiation of human umbilical cord blood-derived mesenchymal stem cells into neural progenitor cells. Materials and Methods: Human umbilical cord blood-derived mesenchymal stem cells were first cultured in Dulbecco’s modified eagle medium supplemented with 10% fetal bovine serum in a humidified incu...

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تاریخ انتشار 2004